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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f726dac7c3c2a12125bc638f768e98ece41511313d423437f5e1b000f1fec29' 
  AND token = 'Tcg9BbfKdBbazoQ3U2m8uC0FcfFcpH5iqK1wqPMKrKI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}