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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a390ab99edea176fd1c55a8a79c8ddd49638e664b4fad1ba80706ee0aaaf475' 
  AND token = '+JkeLx/oD2FDGPgSX/nHzdWp2Ex7UCk2jxjdtcKwMPY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}