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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a453e2e3eee1eaccb708614cf4743a891bc2674eb8291e38560dd85d4f3733a1' 
  AND token = '64KcFE6YWpzVNGhPPjSXz0FK1SbX4/fR/b0tzOnf8sA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}