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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '392a0e1ed6f75a0c60cf4d2611e74abf2c8f6fd0547f6f5918a60c8f9020f334' 
  AND token = '8MS0zYy5UL1m8Hma/06Bf2s93bnCqTYvDM6QlRR6/7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}