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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78225353f752431d038d8df264ff1e2cc78cccc316c95dde9b787a226585c7d8' 
  AND token = '4lCxwulOIOkQe98CX+6rYVnQNgb/DjaNIeyKcyLCh5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}