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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af22cd907f823fbcf9a76f9cb7a0f9dbb736b0dd364b26345ba6fa1738180f7b' 
  AND token = 'W1qpaHLUtKEdjrJdUntRJ4ZFjQOJ2tEyLMt3B+LZm0o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}