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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d24c07ad61d6a2b4a4382ea9be8f0fa66f39329afa21d31624783bdad30a4ab' 
  AND token = 'cCIeRwUN4tptwQa4i1MmQp9wzzGx5OHspa+8ZdeJKC8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}