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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3bfe1888a0882c95d6d92f8a80f0f5d0a48d15e49db38c7c5c205f575ce54533' 
  AND token = '01+3WOAwyIzmLhm/zbs3K7KXE3E6vYkJunCvhlHUaS8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}