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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ca24e2418cd3f23ff0e7d171197a145a286e9f1307c7641d582ff4158d2be08' 
  AND token = '/TVgz3ER5OhsIs6UAxYeWdu+ktwIE3Ywz1NM6x1GdaI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}