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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e75ce667fdfd1130a14e3a5248e931951d7748e48f8a1fa2d6e5f3d71b205fe' 
  AND token = 'oz3CnZ8Rp8A61ObBWv2pf629baY4fOxWBD+viqcsrNQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}