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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7220469dbf928b1c6dd2f7b2781db36190fb78e0f00c0f80f7686f173a6eb940' 
  AND token = 'xlQSsSPGOQ8A1wbT2snn1TSM+CDI5not/wFEYHcyvGg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00095

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}