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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a67362bd25a583825aca53301cb40d08d5826804da23b85fa2e2906a5ad77592' 
  AND token = 'KVZ6thS5mAA0TiuthD+AxAfuXAak1O/wreRkogt/vcE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}