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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6bb0ac2b1fafc5e0d6474535dae8e61cf5e44fc7832897b4fb7f0f336df3b23c' 
  AND token = 'GMxuO+6/xq1wea08I077cZNCF+Isc5wCKC/+yKi5ygI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}