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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed492c4b5b33710022304d005c1f4bc05e9cfe984816fb26644e1be402d67a62' 
  AND token = 'CeOGLQ2sCa7MQWLPREoeZt/lxB6T3MZrduADPMpodfM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}