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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '497c6b8768e7de4f6fa24173cab180351009f63ae3aaaa8cc785b93f6866e1a4' 
  AND token = 'slXSntfHlTvJSki3Wy886kH8zYbK1GPhCa4S2xfgbrQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}