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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd29ca9b6c10fcb7cc2d4090cb427e68ba48b64c199d9879381e3a01b26ae08ba' 
  AND token = 'HsmPAM4RChkpftVQFGPx+gabSTeCCAdx54ZyYXv3FJc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}