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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '241d2e59c5be4e6d2beff7f2a3dea9d460cb1e5166905c98fc6d31c011a54112' 
  AND token = 'OJAT1oce/x7Kv+LsQpBj/MOf+83QF4HKco8rmsGKaP0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}