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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc6c9f93881be1bf49b24f9c4923761537e90667fa75127af1616025d8a681a3' 
  AND token = '++n4m541v9dk8jtm3k+LO+VpFOY75VnDbdHixY0Xurg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}