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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e423fe4d42cf444080f42b8c1527ec48ef8dd4690d414e01d7f449d9386f6cc' 
  AND token = 'oQC/4OcUb/EzFe+dyFJvF+cQ7JyRMUxNx1XXKTZuDWA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}