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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23dc8a563fb5576d5a205f7df4f6ed5b1697c2d66cade4e795fdb85205160a0c' 
  AND token = 'ntF2E0mTVb8/NjPOe1g5Lv2yOCKTcMyo7PXwaix2jbk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}