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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e469c9c0e45a8a31c5e0625ec0d81a062c64c29cb9db338214dc0ca01c66dd2' 
  AND token = '02bFkkWUo0/9vjE86H++r/VZcu8jV7CfVMs0/GS4ZwM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}