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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18810961758b75dd1f422828cdf596a20a335bd31fdd99fa53a30e9e3c1151cf' 
  AND token = 'dsYfPNk6JHn5pqvnvkbsZCTu8m+r9dn7B5YnpYLsRuo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}