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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e545fb307bea41682253e50dd7c56cb8fde7e8f2cfa94277a4110cc8f559c2b' 
  AND token = 'crOPuDbWoSoMnVtPbJ6NdYEH5mm4c7bHPJw9bBBSD/A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00064

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}