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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37ec5fd0f9442a4e6235b0daac7db3801137a430d71f3b63060ed89fa1fc80c1' 
  AND token = 'q1QYjX3Ec2l4xyQO2eAaicvGOTU54NNu79coCWAAUfM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}