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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4422828020068fad1214d2aec675e38bb0e624262de66648f608f37891aa42c5' 
  AND token = 'eskg4U60stY4f+Skr+yAMy0hmoHZl+GkWRpk7cFa7NA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}