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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0b428d965d63b27f72b3acbfb6624decd0dfef12be4e238844825c61f84c2fa' 
  AND token = 'csKQk+BVzwk8HmLdngta535RpZqgUi5zzDs5dF4VEBc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}