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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14d321d85825f63f1f0b5a1daaf8f49695a1e75a8fc53bb80bd06b82f79b75eb' 
  AND token = 'IMjVIP4SoLO27WSM5icBwJtoAmuvquQlyClM+YU3TeM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}