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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1bde8a47641887f195972773c078824bff7ff4682392c1c00b4cb7b41670f733' 
  AND token = '90DiLoQBTT2ga7lLmf9HccneHwoNgrHLn0XUBya1eiE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}