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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0faffb67ef1c8fe36bff3b68e8246aa73e949331fd808dc8fa8868061573b244' 
  AND token = 'eCELMEdGOtTxyGxO2PX+ZecLxRsfiwjKr8DnP1GF5Jg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}