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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '579e7006a6757e0fefe9956e6888959d9903003e391619c4e6b113e3d0a1e31c' 
  AND token = 'KIBE1UCrZvIe2ODql1PfBx0KzNhvwtxP5g56JsaDfq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}