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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df3e1ad31d74c618fbfef4fee5f6baf75d2a4efbad75f03495f6e08da65dc597' 
  AND token = 'illlpGBQnqoduubU1EWd+0okN1i28YKUQS4fheoGnS0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}