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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c791d5ba2780e50943ca85cf7842137134b0528533a1bb768fa6a07a41c58d4d' 
  AND token = 'tySWGhneseKuezQL90DD/yCBnd2FEsB5l4eXI4PHtQk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}