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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '55cbe86e3f236ef0f7bd577d252a931fc939b6f24d7d3163dc2d2020908acadd' 
  AND token = 'Mchlbv4KXcKq4Fc8xS6sPp3SYpyCv4lNCDnN27CqFm4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}