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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16fcbfa9a5f0a4582c639de3ded5a5257694829b81bda9e4610cb0e7c6ac4d74' 
  AND token = 'T0r8epvaw1vJvnKzy/mn463n9ejGbuMbhlVdik968fs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}