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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '659c0ea975d75225226863e0aed3e385d1ebd99f05f1bb8b85443126f58bc640' 
  AND token = 'RMUhO6Wif/myIcOid3jQYP49A1f+MIXvvzd48esGaUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}