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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d89f0150488d44d9fdd8dca5ebed3cdf00042ac1392115ad2a8411c09b22042' 
  AND token = 'FvEd8Qp3t7AGxe1M3Zv7av3BzFea5oLSS7kO0prwCuo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}