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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '320f36c05ae4d75c1c5631545429e2211d68411086ef3bafb03720d51d0552e6' 
  AND token = 'lkeF3g3yDlqDy0DQbMJ1KndAlOMlRyZ9Yogm64FPBlg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}