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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c573c2dd505c4f0742baf95bcf314cdade82dc66a7024e93cb219c7428de059' 
  AND token = 'Re+cEUSUMF7dLxYYiug9ET6OKs9EnZhd7uuLrHnr79c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}