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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45f3634d1d7cdc2ada31211011585c7d4ad8813ba3344dd8a6481084e102b293' 
  AND token = 'x4SqNZ0iqmPrQTp9ZwGIb0qXhFhPWGNzjCbyGvW6nD4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}