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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0e21ce2e7226548f7dc65b31bf88b7c142da75acd45c16c4f05504b31c8c4cb' 
  AND token = 'MrHvQ/4Dm6VZoybcYL1AaxaQryqn7efsTCXxuS6Fp9c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}