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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9aeffe2c8f677b689c6b700a2834b5095969de9ba205e4c40759b21bf70395d' 
  AND token = 'zgiGjFLqMcDmVPMrbPjVQv3P6fBtLN4t6vCQJ32LP+0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}