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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c300c0d77fc3a6675f237fc2534e720d45a8a3fa22a2123900056221cb16ce43' 
  AND token = 'u1edHC2xXsM7nTLyBtB0fb2adbfbW4uqyS5NdlmiwBM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}