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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '917d9affd270b2080d45a7c9a65266972031600f101ae88edb830b13666d219a' 
  AND token = 'IyU146dkcF3myUR2/sCeiRnJW9QS9O+Xd/aCEKHWspU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}