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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce66815849ddec23838dd83a9a4485b1b6e380d3d090a9f69ccd0a65f0292537' 
  AND token = 'BaSW9EwUQp/+SwCyjNmtIL+S3QgMoVSAEWku1rxTyz4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}