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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63483444c69dab9a11bdb4559a14bc0253e2d91fbb71a2d0615c2ff21557c017' 
  AND token = 'mtAsVj5UdtLL2GwJp/yS14VlZ4+osyPRsdaVPtpbTS8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}