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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3b1110070ecc6d3c41a40683d50a99e836982897a93905731e56d5bd606267c' 
  AND token = 'vP4BYE/NZhyXt0C1/0v1ijuTuQE4xXckO23uw3jvbVQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}