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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '153ff06cbc3bba0599e74a950d9912d5f0c451b6a5df0484280fd8b0b6368670' 
  AND token = 'VWZbNV7BAOYL4NscJvfdjFWTKVCEUeZy5PM1MFuR7ZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}