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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b92cfccaa8ef858387a05003da05a183a84500cebd4b3e7e13f9f8c30cbc385' 
  AND token = 'fkKm+yA8rMOa8PX+LB7pmUTNQreumo+CmPTFOGl7SGc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}