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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d709168fd3d50510c657eecf37fd02a987d6ad7941b0438bac1725338ff0229' 
  AND token = 'Soxiz5qYUwrEGjQoYSk5UPeLhX0q0oHJn/iuW4D70yE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}