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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39aaad887770026404878d00895d5c03d8eac64b70b49d8471c5df1764023b98' 
  AND token = 'KB4GUqSLE8Nlmi/SWn46X1HlMul3NZMPiY8+A5sqKVI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}